An X-ray Diffraction Investigation of Poly-e-carbobenzoxy-L-lysine and a Complex Form of Poly-F-methyl-L-glutamate*
ثبت نشده
چکیده
X-ray diagrams from oriented fibers of poly-s-carbobenzoxy-T,-lysine and a n e w form of poly7-methyl-T,-glutamate have been obtained. Spacing calculations and rough equatorial intensity measurements from the poly-s-carbobenzoxy-L-lysine photographs indicate tha t the molecules of this substance have the 3.60-residue a-helix configuration with one molecule in a simple hexagonal unit cell, a 0 ----16.69 and c o = 26.90 ~. The interpretation of the poly-y-methyl-L-glutamate photographs is more difficult, but seems to show that a monoclinic unit cell, a = 29.22, b = 8-39, c ---26.84 A, and fl = 110.0 °, is the only one that satisfactorily explains both the X-ray data and the observed density of the fibers. The structure of the molecules in this form is probably based on the 3.60-residue c~-helix, but there is some evidence which indicates that the helical configuration may be distorted slightly.
منابع مشابه
The Plasticizing Mechanism and Effect of Aluminium Chloride and Glycerin on Poly(vinyl alcohol) Films
Poly(Vinyl Alcohol) (PVA) films were prepared with AlCl3·6H2O/glycerin and AlCl3·6H2O/poly glycerin as two kinds of complex plasticizer. The micromorphology of pure PVA film and PVA films plasticized with complex plasticizer was observed by Scanning Electron Microscope (SEM). The interaction between complex plas...
متن کاملمقایسهی کشت سلولهای استرومایی مغز استخوان با نانوالیاف PLGA پوشش داده شده با ژلاتین و پلی ال لایزین
Background and Objective: Poly D,L-lactic-co-glycolic acid (PLGA) is known as biodegradable and biocompatible polymer. These polymers have recently received much attention in tissue engineering. The aim of this study was to investigate the biological behavior of the bone marrow stromal cells (BMSCs) in culturing with PLGA nanofibers coated with poly-L-lysine or gelatin. Materials and Methods: I...
متن کاملStudy of the inhibitory effects of N-heterocycles, magnesium oxide nanoparticles, nisin and poly-L-lysine on Enterobacter aerogenes (hospital pathogen)
Background: Enterobacter aerogenesis one of the causes of hospital-acquired infections, which its standard strains quickly become resistant to the antibiotics. The discovery of new inhibitory agents against this pathogen is constantly expanding. In this study, the inhibitory effects of several synthetic chemical compounds including magnesium oxide nanoparticles and thiazole, imidazolidine and t...
متن کاملIn vitro Labeling of Neural Stem Cells with Poly-L-Lysine Coated Super Paramagnetic Nanoparticles for Green Fluorescent Protein Transfection
Background: The magnetic nanoparticle-based transfection method is a relatively new technique for delivery of functional genes to target tissues. We aimed to evaluate the transfection efficiency of rat neural stem cell (NSC) using poly-L-lysine hydrobromide (PLL)-coated super paramagnetic iron oxide nanoparticles (SPION). Methods: The SPION was prepared and coated with PLL as transfection agent...
متن کامل